Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_01_ATM_minus_versus_SCID.phenotype_ATM_minus_versus_SCID.cls #ATM_minus_versus_SCID |
| Phenotype | phenotype_ATM_minus_versus_SCID.cls#ATM_minus_versus_SCID |
| Upregulated in class | SCID |
| GeneSet | NCI_CASPASE CASCADE IN APOPTOSIS |
| Enrichment Score (ES) | -0.51562786 |
| Normalized Enrichment Score (NES) | -1.7546066 |
| Nominal p-value | 0.002283105 |
| FDR q-value | 0.3693776 |
| FWER p-Value | 0.801 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | CYCS | 1422484_at 1445484_at | 587 | 2.631 | 0.0311 | No | ||
| 2 | BAX | 1416837_at | 1621 | 1.549 | 0.0180 | No | ||
| 3 | DIABLO | 1417683_at 1425768_at | 3432 | 0.935 | -0.0441 | No | ||
| 4 | GSN | 1415812_at 1436991_x_at 1437171_x_at 1441225_at 1456312_x_at 1456568_at 1456569_x_at | 3485 | 0.925 | -0.0261 | No | ||
| 5 | CRADD | 1427505_a_at 1443430_at | 3924 | 0.833 | -0.0278 | No | ||
| 6 | LMNA | 1421654_a_at 1425472_a_at 1426868_x_at 1452212_at 1457670_s_at | 3954 | 0.827 | -0.0109 | No | ||
| 7 | APAF1 | 1450223_at | 6539 | 0.437 | -0.1194 | No | ||
| 8 | PRF1 | 1451862_a_at | 6879 | 0.400 | -0.1261 | No | ||
| 9 | APP | 1420621_a_at 1427442_a_at 1438373_at 1438374_x_at 1444705_at 1447347_at 1458525_at | 7070 | 0.379 | -0.1264 | No | ||
| 10 | LRDD | 1421397_a_at | 7169 | 0.367 | -0.1228 | No | ||
| 11 | CFL2 | 1418066_at 1418067_at 1431432_at | 7382 | 0.345 | -0.1249 | No | ||
| 12 | CASP4 | 1449591_at | 7991 | 0.288 | -0.1463 | No | ||
| 13 | VIM | 1438118_x_at 1450641_at 1456292_a_at | 9057 | 0.185 | -0.1909 | No | ||
| 14 | BCL2 | 1422938_at 1427818_at 1437122_at 1440770_at 1443837_x_at 1457687_at | 9591 | 0.137 | -0.2122 | No | ||
| 15 | GZMB | 1419060_at | 10282 | 0.079 | -0.2420 | No | ||
| 16 | CASP1 | 1449265_at | 10900 | 0.028 | -0.2696 | No | ||
| 17 | BIRC2 | 1418854_at | 11288 | -0.008 | -0.2871 | No | ||
| 18 | PARP1 | 1422502_at 1422503_s_at 1435368_a_at 1443573_at | 11562 | -0.034 | -0.2988 | No | ||
| 19 | BIRC3 | 1421392_a_at 1425223_at | 12726 | -0.137 | -0.3489 | No | ||
| 20 | TOP1 | 1423474_at 1438495_at 1457573_at 1459672_at | 13721 | -0.227 | -0.3893 | No | ||
| 21 | TNF | 1419607_at | 13820 | -0.238 | -0.3886 | No | ||
| 22 | BID | 1417045_at 1447873_x_at 1448560_at | 15017 | -0.364 | -0.4352 | No | ||
| 23 | DFFB | 1421229_at 1437051_at | 15174 | -0.382 | -0.4339 | No | ||
| 24 | LMNB1 | 1423520_at 1423521_at | 15294 | -0.394 | -0.4307 | No | ||
| 25 | RIPK1 | 1419508_at 1439273_at 1449485_at | 15871 | -0.462 | -0.4468 | No | ||
| 26 | CASP8 | 1424552_at | 16947 | -0.612 | -0.4825 | No | ||
| 27 | LIMK1 | 1417627_a_at 1425836_a_at 1456234_at 1458989_at | 17674 | -0.734 | -0.4995 | Yes | ||
| 28 | SATB1 | 1416007_at 1416008_at 1439203_at 1439449_at 1443284_at 1456902_at | 17826 | -0.766 | -0.4895 | Yes | ||
| 29 | GAS2 | 1429147_at 1435834_at 1438564_at 1450112_a_at | 18240 | -0.860 | -0.4895 | Yes | ||
| 30 | LMNB2 | 1451849_a_at | 18468 | -0.911 | -0.4798 | Yes | ||
| 31 | PTK2 | 1423059_at 1430827_a_at 1439198_at 1440082_at 1441475_at 1443384_at 1445137_at | 18966 | -1.010 | -0.4803 | Yes | ||
| 32 | ACTA1 | 1427735_a_at | 19349 | -1.094 | -0.4736 | Yes | ||
| 33 | SREBF1 | 1426690_a_at | 19353 | -1.096 | -0.4497 | Yes | ||
| 34 | MAP3K1 | 1424850_at | 19820 | -1.242 | -0.4436 | Yes | ||
| 35 | CASP3 | 1426165_a_at 1430192_at 1449839_at | 19993 | -1.310 | -0.4227 | Yes | ||
| 36 | ARHGDIB | 1426454_at | 20525 | -1.576 | -0.4122 | Yes | ||
| 37 | TRAF2 | 1451233_at | 20609 | -1.634 | -0.3801 | Yes | ||
| 38 | CASP6 | 1415995_at 1458715_at | 20811 | -1.766 | -0.3504 | Yes | ||
| 39 | CASP9 | 1426125_a_at 1437537_at 1457816_at | 20906 | -1.849 | -0.3140 | Yes | ||
| 40 | DFFA | 1450885_at 1457564_at | 21032 | -1.942 | -0.2770 | Yes | ||
| 41 | CASP2 | 1448165_at | 21150 | -2.026 | -0.2378 | Yes | ||
| 42 | NUMA1 | 1423974_at 1423975_s_at 1441090_at 1444576_at 1444577_x_at | 21167 | -2.038 | -0.1937 | Yes | ||
| 43 | TRADD | 1429117_at 1439910_a_at 1452622_a_at | 21619 | -2.690 | -0.1551 | Yes | ||
| 44 | TNFRSF1A | 1417291_at | 21718 | -3.039 | -0.0927 | Yes | ||
| 45 | CASP7 | 1426062_a_at 1448659_at | 21858 | -4.665 | 0.0036 | Yes |
